Biography
Brad Niles received his Ph.D. from UC Davis, with a Designated Emphasis in Biotechnology and advanced training in Business Development. He has 15 years of experience in cancer research, and has published more than a dozen scientific papers. In addition, he has managed product development projects for two biotech startups, and is an inventor on numerous RNA-therapeutic patent applications. At ARIZ he has previously served as COO and VP of Research and Development for over 4 years.
Emerging Therapeutics Showcase:
ARIZ Precision Medicine
ARIZ Precision Medicine is focused on the epigenetic changes that occur in the cancerization of a cell to develop targeted therapeutics. With an innovative approach that utilizes the differences in cancer cells, we can specifically kill cancer cells while sparing healthy cells.
PRDM2: A Druggable Target in Lung Cancer
ARIZ is developing a first in class siRNA therapy for lung cancer, targeting a driver gene that is misregulated in 75% of lung cancers with an siRNA packaged in a drug delivery system that achieves significantly tumor growth inhibition.
The PMWC 2022 Emerging Therapeutics Showcase will provide a 15-minute time slot for selected companies and researchers in the CRISPR, Cell and Gene Therapy fields. Major advancements in safer cell- and gene-level editing technologies are bringing us closer toward cures for life-threatening disorders, from cancer to HIV to Huntington’s disease. Cell therapy, in which cellular material such as T cells capable of fighting cancer cells, is injected into a patient, has been demonstrated safe and effective. The popular new CRISPR tool that has been used to edit the genetic code of nearly any organism will have an enormous impact on human health. More than a dozen clinical trials employing CRISPR on human cells are already underway.
- Emerging Therapeutics/Cell Therapy
- Emerging Therapeutics/CVD
- Emerging Therapeutics/Gene Therapy
- Emerging Therapeutics/Immunotherapy
- Emerging Therapeutics/Radiation Therapy