Speaker Profile

PMWC PIONEER AWARD
Leadership role in the Human Genome Project and other large genetic population studies that transformed precision medicine.

Ph.D., Vice President & Chief Scientist, Illumina

Biography
Dr Bentley has focussed on the development and deployment of fast, accurate human whole genome sequencing (WGS) to transform precision medicine at population-scale around the world. Early applications include genetic disease and cancer, exemplified by the completion of the 100,000 genomes project in 2018, which led to the commissioning of WGS as part of the Genomic Medicine Service in the National Health Service in England (NHSE). This work also triggered other larger scale WGS opportunities including UK BioBank, AllofUS and the Our Future Health projects. Prior to Illumina, Dr Bentley was a founder member of the Board of Management at the Sanger Centre where he played a leading role in the Human Genome Project and related international consortia to characterise genetic variation, including the HapMap Project. Dr Bentley laid the foundations for his career in human medical genomics in early studies of molecular genetics of disease at Oxford and Guy’s Hospital, London.


 Session Abstract – PMWC 2023 Silicon Valley

Track 4 - January 25 9.00 A.M.-4.45 P.M.


Track Chair: Cindy Lawley, Olink

  • How New Public-Private Collaboratives Can Catalyze Transformative Health Breakthroughs
    Chair: Keith Yamamoto, UCSF
    - Douglas Friedman, Engineering Biology Research Consortium (EBRC)
    - Jay Keasling, JBEI (Joint BioEnergy Institute)
    - Renee Wegrzyn, ARPA-H
  • Moving Sequencing into the Clinical Setting
    Chair: Charles Chiu, UCSF
    - Charlotte Hobbs, Rady Children’s Hospital
    - Euan Ashley, Stanford University
    - Sivan Bercovici, Karius
    - Heike Sichtig, Foundation Medicine
  • Evolving Sequencing Applications: Spatial Single-Cell Multi-Omics
    Chair: Michael Rhodes, NanoString
    - Chrstina Curtis, Stanford
  • How will Cheap Genome Sequencing Impact Genomic Medicine (PANEL)
    Chair: Euan Ashley, Stanford
    - Shawn Levy, Element Biosciences
    - Aleks Rajkovic, UCSF
    - David Bentley, Illumina
    - Stacey Gabriel, Broad Inst.
    - Sean Hofherr, Fabric Genomics
  • Single-cell, Spatial, and in Situ Technologies
    Chair: Dina Finan, 10x Genomics
    - Carina Emery, Miltenyi Biotec
  • Combining WGS with a AI-based Tumor Enrichment Method
    Chair: Asaf Zviran, C2I
  • Multi-omics Approaches Supporting Clinical Translation
    Chair: Cindy Lawley, Olink
    - Erin Smith, Takeda
    - Si Wu, Stanford
    - Christopher Whelan, J&J
  • Molecular Diagnosis New standard with NGS for Neurological and Infectious Conditions
    Chair: Scott Rabuka, DNA Genotek
    - Forrest Wright, Quadrant Laboratories
    - Frank Middleton, SUNY Upstate Medical University
  • PMWC Showcase
    - Josh Lauer, Ultime
    - Olivier Lucas, Oxford Nanopore
    - Lukasz Boryn, Ardigen