M.D., Ph.D., Professor, Laboratory Medicine and Medicine/Infectious Diseases, UCSF
Biography
Charles Chiu, M.D./Ph.D. is a Professor at UCSF, Director of the UCSF-Abbott Viral Diagnostics and Discovery Center (VDDC), and Associate Director of the UCSF Clinical Microbiology Laboratory. Chiu currently leads a translational research laboratory focused on clinical metagenomic sequencing assay development for infectious diseases and genomic investigation and surveillance of emerging pathogens, including the SARS-CoV-2 coronavirus. He also uses RNA-Seq transcriptome profiling to develop predictive models using machine learning for host response-based diagnosis of COVID-19 and other infections. Chiu’s work is supported by funding from the National Institutes of Health (NIH), Department of Defense, US Centers for Disease Control and Prevention (CDC), philanthropy, and the California Initiative to Advance Precision Medicine. He has authored more than 100 peer-reviewed publications (>20 on COVID-19), holds over 15 patents and patent applications, and serves on the scientific advisory board for Mammoth Biosciences, Danaher Dx, Biomesense, and Flightpath.
Session Abstract – PMWC 2023 Silicon Valley
Track 4 - January 25 9.00 A.M.-4.45 P.M.
Track Chair: Cindy Lawley, Olink
- How New Public-Private Collaboratives Can Catalyze Transformative Health Breakthroughs
Chair: Keith Yamamoto, UCSF
- Douglas Friedman, Engineering Biology Research Consortium (EBRC)
- Jay Keasling, JBEI (Joint BioEnergy Institute)
- Renee Wegrzyn, ARPA-H - Moving Sequencing into the Clinical Setting
Chair: Charles Chiu, UCSF
- Charlotte Hobbs, Rady Children’s Hospital
- Euan Ashley, Stanford University
- Sivan Bercovici, Karius
- Heike Sichtig, Foundation Medicine - Evolving Sequencing Applications: Spatial Single-Cell Multi-Omics
Chair: Michael Rhodes, NanoString
- Chrstina Curtis, Stanford - How will Cheap Genome Sequencing Impact Genomic Medicine (PANEL)
Chair: Euan Ashley, Stanford
- Shawn Levy, Element Biosciences
- Aleks Rajkovic, UCSF
- David Bentley, Illumina
- Stacey Gabriel, Broad Inst.
- Sean Hofherr, Fabric Genomics - Single-cell, Spatial, and in Situ Technologies
Chair: Dina Finan, 10x Genomics
- Carina Emery, Miltenyi Biotec - Combining WGS with a AI-based Tumor Enrichment Method
Chair: Asaf Zviran, C2I
- Multi-omics Approaches Supporting Clinical Translation
Chair: Cindy Lawley, Olink
- Erin Smith, Takeda
- Si Wu, Stanford
- Christopher Whelan, J&J - Molecular Diagnosis New standard with NGS for Neurological and Infectious Conditions
Chair: Scott Rabuka, DNA Genotek
- Forrest Wright, Quadrant Laboratories
- Frank Middleton, SUNY Upstate Medical University - PMWC Showcase
- Josh Lauer, Ultime
- Olivier Lucas, Oxford Nanopore
- Lukasz Boryn, Ardigen
Session Abstract – PMWC 2023 Silicon Valley
Track 3 - January 27 9.00 A.M.-4.15 P.M.
Track Chairs:
Sharon Terry, Genetic Alliance & Alice Rathjen
- PMWC 2023 Award Ceremony:
Pioneer Honoree: David Bentley, Ilumina
- Learnings and Advancements of Population Studies (PANEL)
Chair: Sharon Terry, Genetic Alliance
- David Bentley, Illumina
- Slavé Petrovski, AstraZeneca
- Andrea Ganna, FinnGen
- Robert Wildin, University of Vermont Health
- Alexander Charney, Mount Sinai - Precision Medicine in Understudied Populations
- Ryan Taft, Illumina
- Aimé LUMAKA, WALGEMED - Building Future Precision Care in Qatar
Chair: Khalid Fakhro, Sidra Medicine
- Ziyad M. Hijazi, Sidra Medicine
- Edison T. Liu, The Jackson Labs
- Challenges and Opportunities for National Precision Medicine Initiatives (PANEL)
Chair: Alessandro Riccombeni, Microsoft UK
- Catalina Lopez-Correa, Genome Canada
- Khalid Fakhro, Sidra Medicine
- Framework to Improve the Translation of Genomics into the Clinic (PANEL)
Chair: Kathleen Barnes, Tempus Labs
- Carlos Bustamante, Galatea Bio
- Ora Gordon, Providence
- Abasi Ene-Obong, 54gene - Identifying Relationships Between Disparate Data Sets to Monitor and Control Pathogen Outbreak (PANEL)
Chair: Charles Chiu, UCSF
- Amy Kirby, CDC
- Smruthi Karthikeyan, Caltech - Increasing Diversity in Population Studies
- Manual Rivas - Global Biobank Engine, Stanford Rivas Lab
- The Missing Diversity in Human Epigenomic Studies
- Charles E. Breeze, National Cancer Institute
- The Transition from Genomics to Phenomics in Precision Population Health
- Lee Hood, Phenome Health
Session Abstract – PMWC 2023 Silicon Valley
Track 3 - January 27 9.00 A.M.-4.15 P.M.
New efforts that are currently underway are attempting to leverage waste water surveillance data to monitor status and predict near term direction of pathogen outbreaks via linking it to patient data based on hospital observations. The overall goal is to identify potential pathogens, the related infection status in the population, and to possibly even predict resurgence of a previously identified pathogen via comparison of sequencing data from hundreds of patients to pathogen detection in a broad sampling of waste water across a given area. This panel which includes public health officers, epidemiologists, and research scientists will focus their debate of this timely subject on what promise and predictive value this approach may hold.
