Ph.D., Rehnborg Farquhar Professor of Medicine, Stanford University
Biography
For ~30 years Christopher Gardner has studied what to consume and to avoid for optimal health, and how best to motivate individuals to achieve healthy dietary behaviors. Some of the dozens of human nutrition intervention trials he has conducted include studies of garlic, omega-3 fats, soy phytoestrogens and antioxidants. Among his most cited studies are the A TO Z (JAMA 2007) and the DIETFITS (JAMA 2018) weight loss diet trials. The DIETFITS trial examined the possibility that a 3-SNP multilocus genotype would predict differential weight loss success on a Healthy-Low-Fat vs. a Healthy-Low-Carb diet among more than 600 overweight and obese adults. His interests in this area of personalized nutrition continue with his participation in the Trans-NIH Consortium: Randomized Controlled Trials of Lifestyle Weight Loss Interventions for Genome-wide Association Studies. He is also working on personalized nutrition explorations with other investigators.
Talk
DNA-based Weight Loss Interventions: What Have We Learned?
The 2018 DIETFITS study tested the hypothesis that a 3-SNP genotype pattern would be an effect modifier of weight loss on a healthy low-fat vs. a healthy low-carb diet. The hypothesis was not supported. NIH convened a consortium too look at this question across studies. What have they learned?
Session Abstract – PMWC 2022 Silicon Valley
- Beyond the Human Genome & non-profit Phenome Health
- Lee Hood, Providence Health - UC Precision Medicine Programs: Achievements and Challenges
Session Chair: India Hook-Barnard, EBRC
- Keith Yamamoto, UCSF
- Clara Lajonchere, UCLA
- Frederick J Meyers, UC Davis Health - T2T: Long-Read Sequencing Unlocks The Final Gaps In The Human Genome
- Karen Miga, UCSC - Ultra-rapid Nanopore Genome Sequencing in a Critical Care Setting
- John E. Gorzynski, Stanford
- Precision Approaches to Chronic Disease (PANEL)
Session Chair: Jennifer Lovejoy, Calibrate
- Noel Mueller, Johns Hopkins
- Lee Hood, Providence Health
- Megan Ruth Mahoney, Stanford - DNA-based Weight Loss Interventions: What Have We Learned? (PANEL)
Session Chair: Jennifer Lovejoy, Calibrate
- Lu Qi, Tulane University
- Christopher Gardner, Stanford - Advances in Digital Health, Diabetes and Obesity Management (PANEL)
Session Chair: Mike Snyder, Stanford
- Jessilyn Dunn, Duke University
- Jonathan Long, Stanford
- James Galagan, Boston University - Illumina Accelerator Innovation
Session Chair: Amanda Cashin, Illumina Accelerator
- Trevor Levin, Convergent Genomics
- Rhidi Tariyal, NextGen Jane
- Kareem Barghouti, VastBiome - PMWC Showcase
- Jarret Glasscock, Cofactor Genomics
- David Hanna, Thermo Fisher
