Ph.D., Associate Professor, UCSF
Biography
Marina is an Associate Professor at the Bakar Computational Health Sciences Institute at UCSF. Prior to that she was a Senior Research Scientist at Pfizer after getting her PhD in Biomedical Informatics at Stanford. Dr. Sirota’s research experience spans over 10 years during which she has co-authored over 100 scientific publications. Her research interests lie in developing computational integrative methods and applying these approaches in the context of disease diagnostics and therapeutics. The Sirota laboratory is funded by NIA, NLM, NIAMS, March of Dimes and the Burroughs Wellcome Fund. As a young leader in the field, she has been awarded the AMIA Young Investigator Award in 2017. Dr. Sirota also is the director of the AI4ALL program at UCSF, with the goal of introducing high school girls to applications of AI in biomedicine and serves as the director of outreach and advocacy at the Bakar Computational Health Sciences Institute.
Talk
Novel Insights into Endometriosis through Precision Medicine
Endometriosis, a common, chronic, estrogen-dependent inflammatory disease, derives from uterine endometrium and is a major cause of pelvic pain and infertility. Diagnosis is hampered by complex disease presentation, and medical and surgical therapies are variably effective. Multi-omics approaches are key to developing novel diagnostics and therapeutics for this debilitating disorder and will be discussed herein.
Session Abstract – PMWC 2023 Silicon Valley
Track 3 - January 26 9.00 A.M.-4.30 P.M.
Track Co-Chairs:
Linda Giudice, UCSF
Yoel Sadovsky, UPMC
Researchers have long been recognizing the uniqueness of women’s health and its substantial effect on clinical practice, acknowledging the increasing appreciation of the importance of multidisciplinary approaches to health and disease. In every organ system, there are diseases that are unique to women, more common in women than in men, or characterized by differences in disease course in women compared to men. This Track will focus on the following topics related to Women’s Health:
- PMWC 2023 Award Ceremony:
Pioneer Honoree: Marcia Stefanick, Stanford - Chronic Diseases in Women
- Marcia Stefanick, Stanford (Chronic Disease Prevention) - Marina Sirota, UCSF (Endometriosis) - Stem Cells, Preimplantation and Prenatal Genetics
Chair: Akash Kumar, MyOme, Inc. (Ploygenic risk score)
- Teresa Sparks, UCSF (Prenatal genetic diagnosis)
- Nathan Treff, Genomic Prediction (Reducing polygenic disease risk through embryo selection)
- Precision Health for Mothers and Babies
Chair: David Stevenson, U. of Stanford (Introduction: Towards Precision Health for Mothers and Babies)
- Aleks Rajkovic, UCSF (Genomics of Pregnancy Loss)
- Ivana Maric, Stanford (ML for Early Prediction)
- Nima Aghaeepour, Stanford (AI-Driven Prematurity Taxonomy)
- Precision Health for Mothers and Babies: Components of Pregnancy Health
Chair: Yoel Sadovsky, U. of Pittsburgh (Placental Health)
- Marina Sirota, UCSF (Leveraging Molecular and Clinical Data)
- Brice Gaudilliere, Stanford (Multiomic immune profiling) - Value of Early Risk Prediction, Screening & Digital Intervention in Pre-term birth Avoidance
Chair: Leslie Saltzman, Ovia Health
- Sydney Strickland, Labcorp - Reproductive Aging (PANEL)
Chair: Aleksandar Rajkovic, UCSF
- Diana Laird, UCSF
- Jennifer Garrison, Buck Institute
- Nikolina Lauc, GlycanAge
- Christian Kramme, Gameto - Achieving Equity in Precision Medicine
- Aida Habtezion, Pfizer - Sex Differences
- Noel Bairey Merz, Cedar Sinai (CV disease)
- Danit Ariel, Stanford (Transgender Health and Sex Differences)
- PMWC Showcase:
- Amrie Grammer, Ampel Bio Solutions
