Ph.D., Chief Scientific Officer, Delfi Diagnostics
Biography
Nic recently joined the oncology diagnostics industry after a long career in the pharmaceutical industry leading oncology translational research teams at BMS and Janssen. In this role, he is working with colleagues at Delfi Diagnostics to develop novel assays for the early detection of cancer. This approach utilizes low coverage sequencing of plasma DNA to identify differences in nucleosomal packaging of DNA in cancer and normal cells. Nic obtained his B.Sc. and Ph.D. degrees from the University of London, and completed post-doctoral fellowships at the Memorial Sloan-Kettering Cancer Center and the Massachusetts Institute of Technology. Subsequently, he served as an Assistant Director at the Whitehead/MIT Genome Center, and as a Section Chief at the National Center for Human Genome Research before moving to the biotech and pharmaceutical industry. Nic has authored >80 scientific publications, and has extensive experience in the fields of genomics, molecular biology and cancer research.
Liquid Biopsy Showcase:
Delfi Diagnostics
Delfi Diagnostics is a new venture funded company developing novel mutation-independent tests for the early detection of cancer.
Mutation-Independent Tests For Early Cancer Detection
We describe a new test for early stage cancer that does not require detection of rare somatic mutations, but looks for common secondary effects of these mutations by examining altered plasma DNA fragmentation.
Session Abstract – PMWC 2020 Silicon Valley
Track 7 - January 23 9.00 A.M.-1.15 P.M.
The PMWC 2020 Liquid Biopsy Showcase will provide a 15-minute time slot for selected liquid biopsy companies to present their latest technologies to an audience of leading investors, potential clients, and partners. We will hear from companies that advance the development of screening tests for oncology, immunotherapy, and other areas, based on detection and identification of circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), circulating RNA, circulating microRNAs, or extracellular vesicle (exosomes).
